BIOTEC-03-2016

Microbial chassis platforms with optimized metabolic pathways for industrial innovations through systems biology -

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Call text (as on F&T portal)

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Specific Challenge:

Systems biology deals with the understanding and controlling the complexity of living beings as opposed to studying their constituent parts. As such, systems biology can be considered as a cross-discipline, i.e. the integration of varied types of biological information and the development of models and networks, which together provide greater understanding of the biological system under study. Systems biology relies on cutting-edge technologies, including those in the fields of "omics" (genomics, transcriptomics, proteomics, metabolomics) and bioinformatics, all offering massive amounts of data, most of which remain stored and underexploited. Therefore, it is a growing area of science that builds information from the translation of biological data and strives to transfer knowledge to society in the form of valuable products and processes.

On the other hand, microbes are attractive candidates to serve as cell factories for the production of many valuable compounds useful for the food, feed, fuel, cosmetics and pharmaceutical industries. The current availability of genome sequences and metabolic models offers the adequate resources for the full exploitation of systems biology in industrial biotechnology, which can boost the design of novel and more efficient microbial platforms for the production of industrial compounds through the sound knowledge of their molecular constituents.

Scope

Proposals should use systems biology approaches integrating "omics" data analysis, mathematical modelling and knowledge of interactions between cellular components under different environmental conditions, to enable useful applications for a broader set of microorganisms, while also achieving some of the following:

  • More efficient metabolic pathways of current microbial platforms, adapting them to high performing manufacturing processes
  • Improving existing cell factories or developing new ones with enhanced properties for harsh process conditions in industrial applications
  • Development of efficient cell factories for the industrial production of novel high-value products.
  • Identification of new microbial strains with beneficial characteristics for industrial applications such as those originating from extremophiles and related activities to develop relevant industrial host organisms.

Activities are expected to focus on Technology Readiness Levels 3 to 5. This topic addresses cross-KET activities.

The participation of SMEs is encouraged.

The Commission considers that proposals requesting a contribution from the EU between EUR 5 and 7 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.

Expected Impact:
  • Development of at least two new high added-value products
  • Boosting technological innovation for European industries to keep the leadership in biotechnology in particular in the food, feed, fuel, cosmetics and pharmaceutical industries.
  • An offer of substantial opportunities for an increasing number of SME to uptake innovative research.
  • Development of widely exploitable microbial hosts for the production of industrial goods.

Proposals should include a business case and exploitation strategy, as outlined in the Introduction to the LEIT part of this Work Programme.

Cross-cutting Priorities:

Cross-cutting Key-Enabling Technologies (KETs)

News flashes

2017-07-06

FLASH INFORMATION ON THE CALL RESULTS2017 two-stage TOPICS

Published: 14 October 2015Deadline: 4 May 2017Available budget: 235.47 M€

The Commission has now completed the evaluation of the proposals submitted to the above-mentioned call.The results of the evaluation are as follows:

Number of proposals submitted (including proposals transferred from or to other calls): 107Number of inadmissible proposals: 0Number of ineligible proposals: 0Number of above-threshold proposals: 55Total budget requested for above-threshold proposals:343.422.171 €

We recently informed the applicants about the evaluation results for their proposals.

For questions, please contact the Research Enquiry Service.

2017-05-17

DEADLINE (second stage) of 2017 two-stage topics: 04.05.17107 proposals were submitted in response to this call.The number of proposals for each topics is shown below:

NMBP-04-2017: 7NMBP-05-2017: 10NMBP-06-2017: 14NMBP-07-2017: 6NMBP-12-2017: 6NMBP-14-2017: 2NMBP-15-2017: 10NMBP-19-2017: 7NMBP-20-2017: 6NMBP-22-2017: 8NMBP-25-2017: 3NMBP-28-2017: 2NMBP-29-2017: 2NMBP-35-2017: 4BIOTEC-05-2017: 10BIOTEC-06-2017: 7BIOTEC-07-2017: 3

2017-04-27

FLASH INFORMATION ON THE CALL RESULTS H2020-NMBP-2016-2017 (2017single-stage TOPICS)

Published: 14 October 2015Deadline: 19 January 2017Available budget: CSA : 8.4 M€ + NMBP-13-2017 (X-KET): 15 M€

The Commission has now completed the evaluation of the proposals submitted to the above-mentioned call.The results of the evaluation are as follows:

CSA topicsNumber of proposals submitted (including proposals transferred from or to other calls): 16Number of inadmissible proposals: 1Number of ineligible proposals: 0Number of above-threshold proposals: 10Total budget requested for above-threshold proposals: 14,398,535.25 €

NMBP-13-2017 topicNumber of proposals submitted (including proposals transferred from or to other calls): 62Number of inadmissible proposals: 0Number of ineligible proposals: 0Number of above-threshold proposals: 7Total budget requested for above-threshold proposals: 28,946,700.00 €

We recently informed the applicants about the evaluation results for their proposals.For questions, please contact the Research Enquiry Service.

2017-02-07

Corrigendum - FLASH INFORMATION ON THE CALL RESULTS

H2020-NMBP-2016-2017 (2017 two-stage TOPICS)Please read "Deadline: 27 October 2016"

2017-01-30

FLASH INFORMATION ON THE CALL RESULTS H2020-NMBP-2016-2017 (2017 two-stage TOPICS)

Published: 14 October 2015Deadline: 27 October 2017Available budget: 235,470,000 €

The Commission has now completed the evaluation of the proposals submitted to the above-mentioned call. The following overall thresholds were applied:NMBP-04-2017 8,5/10NMBP-05-2017 8,5/10NMBP-06-2017 8,5/10NMBP-07-2017 8,5/10NMBP-22-2017 8,5/10NMBP-25-2017 8,5/10NMBP-28-2017 8,5/10NMBP-29-2017 8,5/10NMBP-35-2017 8,5/10NMBP-12-2017 8/10NMBP-14-2017 8/10NMBP-15-2017 8/10NMBP-19-2017 8/10NMBP-20-2017 8/10BIOTEC-05-2017 8/10BIOTEC-06-2017 8/10BIOTEC-07-2017 8/10

The results of the evaluation are as follows: Number of proposals submitted (including proposals transferred from or to other calls): 421Number of inadmissible proposals: -Number of ineligible proposals: 2Number of above-threshold proposals: 108Total budget requested for above-threshold proposals: 653,198,271 €We recently informed the applicants about the evaluation results for their proposals. Above-threshold proposals have been invited to submit a full proposal by 4 May 2017.Information on the selected projects will be published on CORDIS after that date. For questions, please contact the Research Enquiry Service.

2017-01-24

Deadline of 2017 single-stage topics: 19.01.2017

A total of 78 proposals were submitted in response to this call. The number of proposals for each topic is shown below:

BIOTEC-08-2017: 2NMBP-13-2017: 62NMBP-16-2017: 2NMBP-31-2017: 2NMBP-34-2017: 7NMBP-37-2017: 1NMBP-38-2017: 2

2016-11-08

Erratum: Deadline (first stage) of 2017 two-stage topics: 27.10.16

2016-11-08

Deadline (first stage) of 2017 two-stage topics: 21.10.16421 proposals were submitted in response to this call.The number of proposals for each topics is shown below:

NMBP-04-2017: 51NMBP-05-2017: 53NMBP-06-2017: 81NMBP-07-2017: 21NMBP-12-2017: 10NMBP-14-2017: 3NMBP-15-2017: 27NMBP-19-2017: 25NMBP-20-2017: 15NMBP-22-2017: 35NMBP-25-2017: 6NMBP-28-2017: 8NMBP-29-2017: 14NMBP-35-2017: 27BIOTEC-05-2017: 16BIOTEC-06-2017: 18BIOTEC-07-2017: 7

2016-09-20
The submission session is now available for: NMBP-13-2017(RIA)
2016-09-20
The submission session is now available for: NMBP-16-2017(CSA), NMBP-37-2017(CSA), NMBP-31-2017(CSA), NMBP-38-2017(CSA), BIOTEC-08-2017(CSA), NMBP-34-2017(CSA)
2016-08-03
The submission session is now available for: NMBP-06-2017(RIA), NMBP-07-2017(RIA), NMBP-05-2017(IA), NMBP-28-2017(RIA), NMBP-19-2017(RIA), NMBP-14-2017(RIA), NMBP-04-2017(RIA), NMBP-15-2017(RIA), NMBP-25-2017(IA), NMBP-12-2017(RIA), NMBP-22-2017(RIA), NMBP-20-2017(IA), NMBP-29-2017(RIA), NMBP-35-2017(RIA)
2016-08-03
The submission session is now available for: BIOTEC-06-2017(IA), BIOTEC-05-2017(RIA), BIOTEC-07-2017(RIA)
2016-07-25

Horizon 2020 Work Programme 2017 update

After the update to the Horizon 2020 Work Programme 2017 of 25 July 2016,the following updates were made:

  • Open Access Data new provisions have been added for 2017 calls with an opening date on or after 26/07/2016.
  • The introduction of the following parts have been modified: o BIOTEC topics under call H2020-NMBP-2016-17. o MODELLING topics under call H2020-NMBP-2016-17
  • The text for evaluation criteria, scoring, threshold and procedure has been clarified.
  • The text for topics NMBP-22-2017, BIOTEC-05-2017, BIOTEC-06-2017 and BIOTEC-07-2017 has been modified.
  • The following two new CSA topics have been added to the call H2020-NMBP-2017: o NMBP-37-2017 Mapping a path to future supply chains o NMBP-38-2017 Support for the enhancement of the impact of PILOT projects.
  • Other Action 5. Exploitation Strategy and Innovation Consultants (ESIC) has been cancelled. Other Action 6. Exploitation Strategy and Innovation Consultants (ESIC) has been changed to other action 5. Exploitation Support Services and the text has been revised.
  • The following new actions have been added: o 8. Study on due diligence and risk assessment of KETs projects by investors o 9. Best practise for identifying and assessing the dual-use issues in enabling technologies research – preliminary study o 10. Addressing dual-use issues in enabling technologies research
  • The indicative budget for call H2020-NMBP-2017 was increased to €253.87 million in 2017.

2016-07-12

Flash Call Info

Call identifier: H2020-NMBP-2016-2017 (2016 Two-stage topics)Call title: Call for Nanotechnologies, Advanced materials, Biotechnology and ProductionPublished: 14 October 2015Deadline: 24 May 2016 17:00:00

Budget available: 174.08 M€

  • BIOTEC-02-2016 03-2016: 32 M€
  • NMBP-01-2016 + 020-2016 + 03-2016 + 23-2016 + 26-2016: 78.08 M€
  • NMBP-09-2016 + 10-2016: 32 M€
  • NMBP-17-2016 + 18-2016: 32M€

The Commission has completed the evaluation of the proposals submitted to the above call. The results of the evaluation are as follows:

TOPICS BIOTEC-02-2016 + 03-20016Number of proposals submitted (including proposals transferred from or to other calls): 17Number of inadmissible proposals: 0Number of ineligible proposals: 0Number of above-threshold proposals: 8Total budget requested for above-threshold proposals: 48,417,925 €

NMBP-01-2016 + 020-2016 + 03-2016 + 23-2016 + 26-2016Number of proposals submitted (including proposals transferred from or to other calls): 36Number of inadmissible proposals: 0Number of ineligible proposals: 0Number of above-threshold proposals: 20Total budget requested for above-threshold proposals: 116,470,292 €

NMBP-09-2016 + 10-2016Number of proposals submitted (including proposals transferred from or to other calls):16Number of inadmissible proposals: 0Number of ineligible proposals: 0Number of above-threshold proposals: 6Total budget requested for above-threshold proposals: 34,039,531 €

NMBP-17-2016 + 18-2016Number of proposals submitted (including proposals transferred from or to other calls): 15Number of inadmissible proposals: 0Number of ineligible proposals: 0Number of above-threshold proposals: 6Total budget requested for above-threshold proposals: 32,301,327 €

We recently informed the applicants about the evaluation results for their proposals.

The number of proposals that can finally be funded depends on the available budget and the formal approval of grant agreements by the Commission.

It is expected that the first grant agreements will be signed by November 2016.

Information on the selected projects will be published on CORDIS after that date.http://cordis.europa.eu/projects/home_en.html

In case of questions, please contact the Research Enquiry Servicehttp://ec.europa.eu/research/enquiries

2016-04-19

An overview of the following evaluation results (flash call info) is now available under the tab Topic conditions and documents:

  • 2016 NMBP single stage topics
  • 2016 NMBP two-stage topics (first stage results)
2016-01-25

Deadline of 2016 single stage topics: 21.01.1638 proposals were submitted in response to this call.The number of proposals for each topics is shown below:

Type of Action: CSA

BIOTEC-04: 3NMBP-24: 1NMBP-27: 2 NMBP-30: 1NMBP-31: 2NMBP-32: 1NMBP-33: 4NMBP-36: 1

Type of Action ERANET-co-FUND

BIOTEC-01: 2NMBP-11: 1NMBP-21: 1

Type of Action RIA (Green Vehicles topic)

NMBP-08: 19

2015-12-14

Deadline (first stage) of 2016 two-stage topics: 08.12.15305 proposals were submitted in response to this call.The number of proposals for each topics is shown below:

NMBP-01-2016: 25NMBP-02-2016: 17NMBP-03-2016: 37NMBP-09-2016: 17NMBP-10-2016: 61NMBP-17-2016: 42NMBP-18-2016: 4NMBP-23-2016: 9NMBP-26-2016: 17BIOTEC-02-2016: 47BIOTEC-03-2016: 29

call topic details
Call status: Closed
Opening date: 2015-10-15 (10 years ago)
Closing date: 2015-12-08 (10 years ago)
Procedure: two-stage

Budget: 32,000,000
Expected grants: not specified
News flashes

This call topic has been appended 17 times by the EC with news.

  • 2017-07-06
    flash information on the call results201...
  • 2017-05-17
    deadline (second stage) of 2017 two-stag...
  • 2017-04-27
    flash information on the call results h2...
  • 2017-02-07
    corrigendum - flash information on the c...
  • 2017-01-30
    flash information on the call results h2...
  • 2017-01-24
    deadline of 2017 single-stage topics: 19...
  • 2016-11-08
    erratum: deadline (first stage) of 2017...
  • 2016-11-08
    deadline (first stage) of 2017 two-stage...
  • 2016-09-20
    the submission session is now available...
  • 2016-09-20
    the submission session is now available...
  • 2016-08-03
    the submission session is now available...
  • 2016-08-03
    the submission session is now available...
  • 2016-07-25
    horizon 2020 work programme 2017 updatea...
  • 2016-07-12
    flash call infocall identifier: h2020-nm...
  • 2016-04-19
    an overview of the following evaluation...
  • 2016-01-25
    deadline of 2016 single stage topics: 21...
  • 2015-12-14
    deadline (first stage) of 2016 two-stage...
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